Biosensors for Brain Trauma and Dual Laser Doppler Flowmetry: Enoxaparin Simultaneously Reduces Stroke-Induced Dopamine and Blood Flow while Enhancing Serotonin and Blood Flow in Motor Neurons of Brain, In Vivo

Biosensors for Brain Trauma and Dual Laser Doppler Flowmetry: Enoxaparin Simultaneously Reduces Stroke-Induced Dopamine and Blood Flow while Enhancing Serotonin and Blood Flow in Motor Neurons of Brain, In Vivo

Neuromolecular Imaging (NMI) based on adsorptive electrochemistry, combined with Dual Laser Doppler Flowmetry (LDF) is presented herein to investigate the brain neurochemistry affected by enoxaparin (Lovenox®), an antiplatelet/antithrombotic medication for stroke victims. NMI with miniature biosenso...

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Bibliographic Details
Main Authors: Edwin H. Kolodny, Patricia A. Broderick
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Sensors
Subjects:
enoxaparin
heparin
blood clots
acute ischemic stroke
motor neurons
dorsal striatum
dopamine
serotonin
homovanillic acid
L-Tryptophan
neuromolecular imaging
electrochemistry
in vivo microvoltammetry
cerebral blood flow
reperfusion
middle cerebral artery occlusion
edema
glycoprotein IIb/IIIa inhibitors
Factor Xa
Factor II
Factor Xa inhibitors
thrombosis
thrombospondin
monoclonal antibodies
platelets
anticoagulants
integrin
dual laser Doppler flowmetry
optic fiber
biochemical sensors
laser sensors
Online Access:http://www.mdpi.com/1424-8220/11/1/138/

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http://www.mdpi.com/1424-8220/11/1/138/

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