Interpreting ambiguous 'trace' results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard.

Interpreting ambiguous 'trace' results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard.

The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity of tests in the absence of a gold standard. The main field diagnostic for Schistosoma mansoni infection, Kato-Katz (KK), is not very s...

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Bibliographic Details
Main Authors: Michelle N Clements, Christl A Donnelly, Alan Fenwick, Narcis B Kabatereine, Sarah C L Knowles, Aboulaye Meité, Eliézer K N'Goran, Yolisa Nalule, Sarah Nogaro, Anna E Phillips, Edridah Muheki Tukahebwa, Fiona M Fleming
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5738141?pdf=render

Internet

http://europepmc.org/articles/PMC5738141?pdf=render

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