Broad MICA/B expression in the small bowel mucosa: a link between cellular stress and celiac disease.

Broad MICA/B expression in the small bowel mucosa: a link between cellular stress and celiac disease.

The MICA/B genes (MHC class I chain related genes A and B) encode for non conventional class I HLA molecules which have no role in antigen presentation. MICA/B are up-regulated by different stress conditions such as heat-shock, oxidative stress, neoplasic transformation and viral infection. Particul...

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Bibliographic Details
Main Authors: Yessica L Allegretti, Constanza Bondar, Luciana Guzman, Eduardo Cueto Rua, Nestor Chopita, Mercedes Fuertes, Norberto W Zwirner, Fernando G Chirdo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3772809?pdf=render

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http://europepmc.org/articles/PMC3772809?pdf=render

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