Down-Regulation of miR-34a-5p Potentiates Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemic Myocardial Infarction by Stimulating the Expression of C1q/Tumor Necrosis Factor-Related Protein-9

Down-Regulation of miR-34a-5p Potentiates Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemic Myocardial Infarction by Stimulating the Expression of C1q/Tumor Necrosis Factor-Related Protein-9

Adipose-derived stem cells (ADSCs) have shown great promise for the treatment of myocardial infarction (MI), although their potential therapeutic mechanism remains poorly understood. Growing evidence has implicated microRNAs (miRNAs or miRs) in the biological processes whereby ADSCs could ameliorate...

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Bibliographic Details
Main Authors: Chi-Feng Weng, Ching-Feng Wu, Shao-Hsuan Kao, Jeen-Chen Chen, Hui-Han Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Physiology
Subjects:
myocardial infarction
microRNA-34a-5p
C1q/tumor necrosis factor-related protein-9
adipose-derived stem cells
proliferation
migration
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01445/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.01445/full

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