SMOC can act as both an antagonist and an expander of BMP signaling

SMOC can act as both an antagonist and an expander of BMP signaling

The matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically from vertebrates to arthropods. We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of its receptor via activation of mitogen-activated protein kinase (MA...

Full description

Bibliographic Details
Main Authors: J Terrig Thomas, D Eric Dollins, Kristin R Andrykovich, Tehyen Chu, Brian G Stultz, Deborah A Hursh, Malcolm Moos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
BMP Signaling
SMOC
skeletal joint
drosophila wing
Online Access:https://elifesciences.org/articles/17935

Internet

https://elifesciences.org/articles/17935

Similar Items