A lung segmental model of chronic Pseudomonas infection in sheep.

Chronic lung infection with Pseudomonas aeruginosa is a major contributor to morbidity, mortality and premature death in cystic fibrosis. A new paradigm for managing such infections is needed, as are relevant and translatable animal models to identify and test concepts. We sought to improve on limit...

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Bibliographic Details
Main Authors: David Collie, John Govan, Steven Wright, Elisabeth Thornton, Peter Tennant, Sionagh Smith, Catherine Doherty, Gerry McLachlan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706528?pdf=render