Computational and experimental prediction of human C-type lectin receptor druggability

Computational and experimental prediction of human C-type lectin receptor druggability

Mammalian C-type lectin receptors are involved in many aspects of immune cell regulation such as pathogen recognition, clearance of apoptotic bodies and lymphocyte homing. Despite a great interest in modulating C-type lectin receptor recognition of carbohydrates, the number of specific molecular pro...

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Bibliographic Details
Main Authors: Jonas eAretz, Eike-Christian eWamhoff, Jonas eHanske, Dario eHeymann, Christoph eRademacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
DC-SIGN
inhibitor
C-type lectin receptors
langerin
druggability
MCL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00323/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00323/full

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