Drosophila Smad2 opposes Mad signaling during wing vein development.

In the vertebrates, the BMP/Smad1 and TGF-beta/Smad2 signaling pathways execute antagonistic functions in different contexts of development. The differentiation of specific structures results from the balance between these two pathways. For example, the gastrula organizer/node of the vertebrates req...

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Bibliographic Details
Main Authors: Veronika Sander, Edward Eivers, Renee H Choi, Edward M De Robertis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2860994?pdf=render