Dual size-exclusion chromatography for efficient isolation of extracellular vesicles from bone marrow derived human plasma

Dual size-exclusion chromatography for efficient isolation of extracellular vesicles from bone marrow derived human plasma

Abstract Isolation of pure extracellular vesicles (EVs), especially from blood, has been a major challenge in the field of EV research. The presence of lipoproteins and soluble proteins often hinders the isolation of high purity EVs upon utilization of conventional separation methods. To circumvent...

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Bibliographic Details
Main Authors: Jik-Han Jung, Woojin Back, Junyong Yoon, Hyeonjeong Han, Ka-Won Kang, Byeonghyeon Choi, Hyesun Jeong, Jaena Park, Hyunku Shin, Woojune Hur, Yeonho Choi, Sunghoi Hong, Hyun Koo Kim, Yong Park, Ji-Ho Park
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80514-8

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https://doi.org/10.1038/s41598-020-80514-8

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