Exons 19 and 21 of Epidermal Growth Factor Receptor Are Highly Conserved in Squamous Cell Cancer of the Head and Neck

Exons 19 and 21 of Epidermal Growth Factor Receptor Are Highly Conserved in Squamous Cell Cancer of the Head and Neck

Objective. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibition (TKI) is a promising treatment in upper aerodigestive malignancies. EGFR inhibitors might be more effective in patients whose tumors harbor specific EGFR mutations. The presence of specific EFGR mutations is predictive of...

Full description

Bibliographic Details
Main Authors:	Matthew Carlson, Beverly Wuertz, Jizhen Lin, Randy Taylor, Frank Ondrey
Format:	Article
Language:	English
Published:	Hindawi Limited 2009-01-01
Series:	International Journal of Otolaryngology
Online Access:	http://dx.doi.org/10.1155/2009/649615

Similar Items

Significance of human epidermal growth factor receptor 2 neu immunostain in head and neck squamous cell carcinoma
by: Ponkhi Doley, et al.
Published: (2020-01-01)

Association of Epidermal Growth Factor Receptor (EGFR) with Tumor Location and Clinicopathological Aspect in Head and Neck Squamous Cell Carcinoma
by: I Nyoman Diwiya Abdi Nuratna, et al.
Published: (2016-06-01)

Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells
by: Yu-Chin Lin, et al.
Published: (2012-06-01)

Investigation of the hypoxia activated epidermal growth factor receptor and signal transduction pathway in head and neck squamouse cell lines
by: Su Chih-Sheng, et al.
Published: (2009)

Human epidermal growth factor receptor-2 expression in head and neck squamous cell carcinoma: A potential for targeted therapy?
by: Ravi C Nayar, et al.
Published: (2016-01-01)

Evaluation of methylation profiles of an epidermal growth factor receptor gene in a head and neck squamous cell carcinoma patient group
by: Mutlu M, et al.
Published: (2021-03-01)

The effects of reactive oxygen species on activated epidermal growth factor receptor and cell invasion of head and neck squamouse cell lines
by: Li Shih Yun, et al.
Published: (2008)

RhoC Mediates Epidermal Growth Factor-Stimulated Migration and Invasion in Head and Neck Squamous Cell Carcinoma
by: Zohra Tumur, et al.
Published: (2015-01-01)

Targeting the Mevalonate Pathway Enhances the Efficacy of Epidermal Growth Factor Receptor – Tyrosine Kinase Inhibitors in Head and Neck Squamous Cell Carcinoma
by: Mukhtar, Lenah
Published: (2020)

Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response
by: Sean P. Korpela, et al.
Published: (2021-01-01)

Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma
by: Fertig Elana J, et al.
Published: (2012-05-01)

An allelotype of squamous carcinoma of the head and neck
by: Ah-See, Kim Wong
Published: (1994)

Identification of the mechanism involved in regulating epidermal growth factor-induced fibronectin expression in head and neck squamous cell carcinoma
by: Jing-HeWang, et al.
Published: (2017)

CORRELATION OF P21 EXPRESSION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA WITH CLINICOPATHOLOGIC AND PROGNOSTIC PARAMETERS
by: Safana Sadaf, et al.
Published: (2015-11-01)

Radiological and Clinical Features associated with Epidermal Growth Factor Receptor Mutation Status of Exon 19 and 21 in Lung Adenocarcinoma
by: Zhang Shi, et al.
Published: (2017-03-01)

Exosomes in Head and Neck Squamous Cell Carcinoma
by: Cheng Xiao, et al.
Published: (2019-09-01)

Cutaneous Squamous Cell Carcinoma of the Head and Neck
by: Vivek V. Gurudutt, et al.
Published: (2011-01-01)

Immunotherapy in Head and Neck Squamous Cell Cancer
by: Nerina Denaro, et al.
Published: (2018-12-01)

Prognostic biomarkers for head and neck squamous carcinoma
by: El-Attar, Radien
Published: (2013)

Prognostic Worth of Epidermal Growth Factor Receptor (EGFR) in Patients with Head and Neck Tumors
by: Precious Barnes, et al.
Published: (2020-01-01)

Efficacy of gefitinib in epidermal growth factor receptor-activating mutation-positive nonsmall cell lung cancer: Does exon 19 deletion differ from exon 21 mutation?
by: Amit Joshi, et al.
Published: (2018-01-01)

Inclusion of hnRNP L Alternative Exon 7 Is Associated with Good Prognosis and Inhibited by Oncogene SRSF3 in Head and Neck Squamous Cell Carcinoma
by: Lingfeng Xu, et al.
Published: (2019-01-01)

The role of cyclooxygenase-2 and pyruvate dehydrogenase kinase 1 in epidermal growth factor-enhanced head and neck squamous cell carcinoma metastasis
by: Jinn-YuanHsu, et al.
Published: (2015)

Toxic epidermal necrolysis associated with nivolumab treatment for head and neck cancer
by: Keiichi Koshizuka, et al.
Published: (2021-02-01)

Transcriptional Activity of Human Epidermal Growth Factor Receptor Family and Angiogenesis Effectors in Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma and Correlation with Patient Outcome
by: George Pentheroudakis, et al.
Published: (2009-01-01)

Epidermal growth factor receptor inhibition reduces angiogenesis via hypoxia-inducible factor-1α and Notch1 in head neck squamous cell carcinoma.
by: Wei-Ming Wang, et al.
Published: (2015-01-01)

THE PROGNOSTIC POTENTIAL OF THE EPIDERMAL GROWTH FACTOR RECEPTOR AND NUCLEAR FACTOR KAPPA B PATHWAYS AND ASSOCIATED THERAPEUTIC STRATEGIES IN PATIENTS WITH SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
by: Wirth, Pamela
Published: (2010)

Editorial for the Special Issue “Squamous Cell Cancer of the Head and Neck—Time to Arrive in the 21st Century of Oncology”
by: Sven Perner, et al.
Published: (2021-02-01)

Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)
by: Alexandra Iulia Irimie-Aghiorghiesei, et al.
Published: (2019-11-01)

A Study of Head and Neck Squamous Cell Carcinoma Adhesion Mediated by Glycosphingolipids
by: Wood, S. Matthew
Published: (2011)

Epidermal growth factor receptor pathway as therapeutic development in head and neck cancers: present and future
by: Chancellor E. Donald, et al.
Published: (2011-12-01)

The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications
by: Azria David, et al.
Published: (2006-05-01)

Molecular features of head and neck squamous cell carcinoma
by: G. V. Kakurina, et al.
Published: (2018-09-01)

MAPKs activation in head and neck squamous cell carcinomas
by: Daniele Maggioni, et al.
Published: (2011-11-01)

Head and Neck Squamous Cell Carcinoma: Epigenetic Landscape
by: Kamila Romanowska, et al.
Published: (2021-12-01)

Re-irradiation for head and neck squamous cell carcinoma
by: Rony Benson, et al.
Published: (2017-03-01)

Genetic alterations in head and neck squamous cell carcinomas
by: Nagai M.A.
Published: (1999-01-01)

Sialic acids in squamous cell carcinoma of the head and neck
by: Izabela Bronikowska, et al.
Published: (2016-12-01)

Diagnosis and Radioimmunotherapy of Head and Neck Squamous Cell Carcinomas
by: Ekberg, Tomas
Published: (2008)

Precision Therapy of Head and Neck Squamous Cell Carcinoma
by: D’Silva, N.J, et al.
Published: (2018)