Exons 19 and 21 of Epidermal Growth Factor Receptor Are Highly Conserved in Squamous Cell Cancer of the Head and Neck

Objective. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibition (TKI) is a promising treatment in upper aerodigestive malignancies. EGFR inhibitors might be more effective in patients whose tumors harbor specific EGFR mutations. The presence of specific EFGR mutations is predictive of...

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Bibliographic Details
Main Authors: Matthew Carlson, Beverly Wuertz, Jizhen Lin, Randy Taylor, Frank Ondrey
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:International Journal of Otolaryngology
Online Access:http://dx.doi.org/10.1155/2009/649615