Simultaneous targeting therapy for lung metastasis and breast tumor by blocking the NF-κB signaling pathway using Celastrol-loaded micelles

Simultaneous targeting therapy for lung metastasis and breast tumor by blocking the NF-κB signaling pathway using Celastrol-loaded micelles

Metastasis is one of the major obstacles for successful therapy of breast tumor. To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with αvβ3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were...

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Bibliographic Details
Main Authors: Yue Zhao, Yanan Tan, Tingting Meng, Xuan Liu, Yun Zhu, Yun Hong, Xiqin Yang, Hong Yuan, Xuan Huang, Fuqiang Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
simultaneous targeting
metastasis
tetraiodothyroacetic acid
breast tumor
drug delivery system
Online Access:http://dx.doi.org/10.1080/10717544.2018.1425778

Internet

http://dx.doi.org/10.1080/10717544.2018.1425778

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