Characteristics and Risk Factors of Cytokine Release Syndrome in Chimeric Antigen Receptor T Cell Treatment

Characteristics and Risk Factors of Cytokine Release Syndrome in Chimeric Antigen Receptor T Cell Treatment

Clinical trials have confirmed that chimeric antigen receptor (CAR) T cell therapies are revolutionizing approaches for treating several relapsed or refractory hematological tumors. Cytokine release syndrome (CRS) is an adverse event with high incidence during CAR-T treatment. A further understandin...

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Bibliographic Details
Main Authors: Zhiling Yan, Huanxin Zhang, Jiang Cao, Cheng Zhang, Hui Liu, Hongming Huang, Hai Cheng, Jianlin Qiao, Ying Wang, Yan Wang, Lei Gao, Ming Shi, Wei Sang, Feng Zhu, Depeng Li, Haiying Sun, Qingyun Wu, Yuekun Qi, Hujun Li, Xiangmin Wang, Zhenyu Li, Hong Liu, Junnian Zheng, Wenbin Qian, Xi Zhang, Kailin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
cytokine release syndrome
chimeric antigen receptor T cell
acute lymphocyte leukemia
lymphoma
multiple myeloma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.611366/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.611366/full

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