Cutaneous Effects of In Utero and Lactational Exposure of C57BL/6J Mice to 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin

Cutaneous Effects of In Utero and Lactational Exposure of C57BL/6J Mice to 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin

To determine the cutaneous effects of in utero and lactational exposure to the AHR ligand 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD), pregnant C57BL/6J mice were exposed by gavage to a vehicle or 5 μg TCDD/kg body weight at embryonic day 12 and epidermal barrier formation and func...

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Bibliographic Details
Main Authors: Jyoti Bhuju, Kristin M. Olesen, Clarisse S. Muenyi, Tejesh S. Patel, Robert W. Read, Lauren Thompson, Omar Skalli, Qi Zheng, Elizabeth A. Grice, Carrie Hayes Sutter, Thomas R. Sutter
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Toxics
Subjects:
TCDD: 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin
dioxin
AHR: aryl hydrocarbon receptor
skin
epidermis
atopic dermatitis
Online Access:https://www.mdpi.com/2305-6304/9/8/192

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https://www.mdpi.com/2305-6304/9/8/192

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