Reconstituted high density lipoprotein enriched with the polyene antibiotic amphotericin B

Reconstituted high density lipoprotein enriched with the polyene antibiotic amphotericin B

The polyene antibiotic amphotericin B (AMB) is an effective antifungal agent whose therapeutic potential is limited by poor aqueous solubility and toxicity toward host tissues. Addition of apolipoprotein A-I to a multilamellar phospholipid vesicle dispersion containing 20% (w/w) AMB induces the form...

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Bibliographic Details
Main Authors: Michael N. Oda, Peter L. Hargreaves, Jennifer A. Beckstead, Katherine A. Redmond, Rik van Antwerpen, Robert O. Ryan
Format: Article
Language:English
Published: Elsevier 2006-02-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein
phospholipid
Saccharomyces cerevisiae
fungus
Candida albicans
red blood cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520336270

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http://www.sciencedirect.com/science/article/pii/S0022227520336270

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