Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X

Background. Dysregulation of microRNAs may contribute to the progression of trauma-induced coagulopathy (TIC). We aimed to explore the biological function that miRNA-24-3p (miR-24) might have in coagulation factor deficiency after major trauma and TIC. Methods. 15 healthy volunteers and 36 severe tr...

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Bibliographic Details
Main Authors: Lu-Jia Chen, Lian Yang, Xing Cheng, Yin-Kai Xue, Li-Bo Chen
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2017/3649693