Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis

Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis

Multiple myeloma (MM) is a malignant neoplasm of plasma, and exhibits several harmful effects including osteolytic injuries, hypercalcemia, and immune dysfunction. Many patients with MM succumb to the underlying malignancy. An S-phase kinase-related protein 2 (Skp2) inhibitor, designated SKPin C1, h...

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Bibliographic Details
Main Authors:	Ying Yang, Wei Yan, Zhuogang Liu, Minjie Wei
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2019-04-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Skp2 SKPin C1 Multiple myeloma p27 Ubiquitination
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000500605&lng=en&tlng=en

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