Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis

Multiple myeloma (MM) is a malignant neoplasm of plasma, and exhibits several harmful effects including osteolytic injuries, hypercalcemia, and immune dysfunction. Many patients with MM succumb to the underlying malignancy. An S-phase kinase-related protein 2 (Skp2) inhibitor, designated SKPin C1, h...

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Bibliographic Details
Main Authors: Ying Yang, Wei Yan, Zhuogang Liu, Minjie Wei
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2019-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
p27
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000500605&lng=en&tlng=en