In Vitro Characterization of a Biaryl Amide Anti-virulence Compound Targeting Candida albicans Filamentation and Biofilm Formation

In Vitro Characterization of a Biaryl Amide Anti-virulence Compound Targeting Candida albicans Filamentation and Biofilm Formation

We have previously identified a small molecule compound, N-[3-(allyloxy)-phenyl]-4-methoxybenzamide (9029936), that exerts potent inhibitory activity against filamentation and biofilm formation by the Candida albicans SC5314 strain and represents a lead candidate for the development of anti-virulenc...

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Bibliographic Details
Main Authors: Jesus A. Romo, Christopher G. Pierce, Marisol Esqueda, Chiung-Yu Hung, Stephen. P. Saville, Jose L. Lopez-Ribot
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Candida albicans
candidiasis
biofilms
filamentation
anti-virulence drugs
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00227/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00227/full

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