MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice.

Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E knockout (apoE-/-) mice and explore the potential me...

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Bibliographic Details
Main Authors: Ping-Ping He, Xin-Ping OuYang, Yuan Li, Yun-Cheng Lv, Zong-Bao Wang, Feng Yao, Wei Xie, Yu-Lin Tan, Liang Li, Min Zhang, Gang Lan, Duo Gong, Hai-Peng Cheng, Hui-Juan Zhong, Dan Liu, Chong Huang, Zhao-Xia Li, Xi-Long Zheng, Wei-Dong Yin, Chao-Ke Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580638?pdf=render