MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development
Abstract Background Identification of novel MDM2 or p53 binding proteins may reveal undefined oncogenes, tumor suppressors, signaling pathways and possible treatment targets. Methods By means of immunoprecipitation and Mass Spectrometry analysis, we aimed to identify novel regulators of the MDM2-p53...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-02-01
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| Series: | Journal of Experimental & Clinical Cancer Research |
| Online Access: | http://link.springer.com/article/10.1186/s13046-018-0693-7 |