Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?

Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?

Cholangiocarcinoma is a lethal disease with scarce response to current systemic therapy. The rare occurrence and large heterogeneity of this cancer, together with poor knowledge of its molecular mechanisms, are elements contributing to the difficulties in finding an appropriate cure. Cholangiocytes...

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Bibliographic Details
Main Authors: Leonardo Baiocchi, Ilaria Lenci, Martina Milana, Lindsey Kennedy, Keisaku Sato, Wenjun Zhang, Burcin Ekser, Ludovica Ceci, Vik Meadows, Shannon Glaser, Gianfranco Alpini, Heather Francis
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
cholangiocarcinoma
cAMP
cholangiocytes
proliferation
PKA
secretin
Online Access:https://www.mdpi.com/2073-4409/10/7/1692

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https://www.mdpi.com/2073-4409/10/7/1692

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