Scanning single-molecule counting system for Eprobe with highly simple and effective approach.

Here, we report a rapid and ultra-sensitive detection technique for fluorescent molecules called scanning single molecular counting (SSMC). The method uses a fluorescence-based digital measurement system to count single molecules in a solution. In this technique, noise is reduced by conforming the s...

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Bibliographic Details
Main Authors: Takeshi Hanami, Tetsuya Tanabe, Takuya Hanashi, Mitsushiro Yamaguchi, Hidetaka Nakata, Yasumasa Mitani, Yasumasa Kimura, Takahiro Soma, Kengo Usui, Michiko Isobe, Takashi Ogawa, Masayoshi Itoh, Yoshihide Hayashizaki, Seiji Kondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243319