Suppressive effects of anthrax lethal toxin on megakaryopoiesis.

Suppressive effects of anthrax lethal toxin on megakaryopoiesis.

Anthrax lethal toxin (LT) is a major virulence factor of Bacillus anthracis. LT challenge suppresses platelet counts and platelet function in mice, however, the mechanism responsible for thrombocytopenia remains unclear. LT inhibits cellular mitogen-activated protein kinases (MAPKs), which are vital...

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Bibliographic Details
Main Authors: Po-Kong Chen, Hsin-Hou Chang, Guan-Ling Lin, Tsung-Pao Wang, Yi-Ling Lai, Ting-Kai Lin, Ming-Chun Hsieh, Jyh-Hwa Kau, Hsin-Hsien Huang, Hui-Ling Hsu, Chi-Yuan Liao, Der-Shan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3605335?pdf=render

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http://europepmc.org/articles/PMC3605335?pdf=render

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