Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress

Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress

Ultraviolet B radiation (UVB) is an environmental complete carcinogen, which induces and promotes keratinocyte carcinomas, the most common human malignancies. UVB induces the formation of cyclobutane pyrimidine dimers (CPDs). Repairing CPDs through nucleotide excision repair is slow and error-prone...

Full description

Bibliographic Details
Main Authors: Csaba Hegedűs, Tamás Juhász, Eszter Fidrus, Eszter Anna Janka, Gábor Juhász, Gábor Boros, György Paragh, Karen Uray, Gabriella Emri, Éva Remenyik, Péter Bai
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
UVB
CPD
Photolyase mRNA
Mitochondria
Keratinocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720310132

Internet

http://www.sciencedirect.com/science/article/pii/S2213231720310132

Similar Items