SARS Virus Papain-Like Protease: A Mysterious Weapon

SARS Virus Papain-Like Protease: A Mysterious Weapon

Introduction: Papain-like protease (PLpro) of SARS-CoV in association with 3Chemotrypsin-like protease (3CLpro or Mpro) are two proteases which auto-proteolyze replicase polyproteins pp1a/pp1ab. These poly-proteins are translated from ORF1a/ORF1b of the virus genome. Cleavage of pp1a/pp1ab releases...

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Bibliographic Details
Main Authors: Reza Nejat, Ahmad Shahir Sadr
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-07-01
Series:Journal of Biostatistics and Epidemiology
Subjects:
Papain-like protease;
Ubiquitination
Interferon stimulated gene
15 (ISG15)
Deubiquitination
SARS coronavirus
Online Access:https://jbe.tums.ac.ir/index.php/jbe/article/view/354

Internet

https://jbe.tums.ac.ir/index.php/jbe/article/view/354

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