Hypo-Expression of Tuberin Promotes Adenomyosis via the mTOR1-Autophagy Axis

Adenomyosis (AM) is a disease in which endometrial tissue invades the myometrium and has a 10–60% prevalence in reproductive-aged women. TSC2 regulates autophagy via mTOR1 signalling in colorectal cancer and endometrial carcinoma. Dysregulation of autophagy is implicated in adenomyosis pathogenesis....

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Bibliographic Details
Main Authors: Ni-Hao Gu, Guo-Jing Li, Bing-Xin Yang, Min You, Yu Lin, Feng Sun, Hong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.710407/full