Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice

Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice

Abstract Background Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. It is unclear whether inhibition of sodium glucose cotransporter 2 (SGLT2) in subjects with type 2 diabetes (T2DM) could affect PVAT characters, and whether the SGLT2 inhibitor...

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Bibliographic Details
Main Authors: Kentaro Mori, Kyoichiro Tsuchiya, Suguru Nakamura, Yasutaka Miyachi, Kumiko Shiba, Yoshihiro Ogawa, Kenichiro Kitamura
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cardiovascular Diabetology
Subjects:
Vascular remodeling
Perivascular adipose tissue
Healthy adipose expansion
Cuff injury
Online Access:http://link.springer.com/article/10.1186/s12933-019-0886-1

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http://link.springer.com/article/10.1186/s12933-019-0886-1

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