Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.

Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA rather than protein levels. Many variants remain wi...

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Bibliographic Details
Main Authors: Amy L Stark, Ronald J Hause, Lidija K Gorsic, Nirav N Antao, Shan S Wong, Sophie H Chung, Daniel F Gill, Hae K Im, Jamie L Myers, Kevin P White, Richard Baker Jones, M Eileen Dolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3974641?pdf=render