Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

Abstract Background Mesenchymal stem cells (MSCs) attenuate lung injury in experimental models of bronchopulmonary dysplasia (BPD). Stromal derived factor-1 (SDF-1), a chemokine secreted by MSCs, modulates angiogenesis and stem cell recruitment. Here we tested the hypothesis that SDF-1 mediates MSC...

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Bibliographic Details
Main Authors: Joel Reiter, Shelley Drummond, Ibrahim Sammour, Jian Huang, Victoria Florea, Polliana Dornas, Joshua M. Hare, Claudia O. Rodrigues, Karen C. Young
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Respiratory Research
Online Access:http://link.springer.com/article/10.1186/s12931-017-0620-z

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http://link.springer.com/article/10.1186/s12931-017-0620-z

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