Comparative proteomic approach identifies PKM2 and cofilin-1 as potential diagnostic, prognostic and therapeutic targets for pulmonary adenocarcinoma.

Lung cancer is the leading cause of cancer-related death in the world. Non-small cell lung carcinomas (Non-SCLC) account for almost 80% of lung cancers, of which 40% were adenocarcinomas. For a better understanding of the molecular mechanisms behind the development and progression of lung cancer, pa...

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Bibliographic Details
Main Authors: Xing-chen Peng, Feng-ming Gong, Yu-wei Zhao, Liang-xue Zhou, Ying-wei Xie, Hong-li Liao, Hong-jun Lin, Zhi-yong Li, Ming-hai Tang, Ai-ping Tong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210781?pdf=render