Molecular Cochaperones: Tumor Growth and Cancer Treatment

Molecular chaperones play important roles in all cellular organisms by maintaining the proteome in an optimally folded state. They appear to be at a premium in cancer cells whose evolution along the malignant pathways requires the fostering of cohorts of mutant proteins that are employed to overcome...

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Bibliographic Details
Main Author: Stuart K. Calderwood
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2013/217513