The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins

Atherosclerosis results from the accumulation of lipoproteins in the vascular wall. Here, Thierer et al. report the design of a chemiluminescent reporter for atherogenic lipoproteins using fusion of apolipoprotein-B to a luciferase enzyme, and find it bears potential for the identification of regula...

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Bibliographic Details
Main Authors: James H. Thierer, Stephen C. Ekker, Steven A. Farber
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11259-w