Two hits to the renin‐angiotensin system may play a key role in severe COVID‐19

Abstract The spike glycoprotein on the virion surface docking onto the angiotensin‐converting enzyme (ACE) 2 dimer is an essential step in the process of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection in human cells—involves downregulation of ACE2 expression with systemic ren...

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Bibliographic Details
Main Authors: Yu‐Hsin Tseng, Rei‐Cheng Yang, Tzong‐Shi Lu
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.1002/kjm2.12237