TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

Abstract Background An acute and drastic inflammatory response characterized by the production of inflammatory mediators is followed by stroke, including SAH. Overactivation of microglia parallels an excessive inflammatory response and worsened brain damage. Previous studies indicate that TSG-6 has...

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Bibliographic Details
Main Authors: Ran Li, Wenchao Liu, Jian Yin, Yunchang Chen, Shenquan Guo, Haiyan Fan, Xifeng Li, Xin Zhang, Xuying He, Chuanzhi Duan
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Neuroinflammation
Subjects:
Subarachnoid hemorrhage
Early brain injury
Microglial polarization
TSG-6
Anti-inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1279-1

Internet

http://link.springer.com/article/10.1186/s12974-018-1279-1

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