Oxygen Modulates the Effectiveness of Granuloma Mediated Host Response to Mycobacterium tuberculosis: a Multi-scale Computational Biological Approach
In several mammalian hosts, including non-human primates, Mycobacterium tuberculosis granulomas are often hypoxic, although this has not been observed in wild type murine infection models. Mtb associated granuloma formation can be viewed as a structural immune response that can contain and halt the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-02-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00006/full |