The pH of chemistry assays plays an important role in monoclonal immunoglobulin interferences

Objectives: Immunoglobulin paraproteins can interfere with multiple chemistry assays. We want to investigate the mechanisms of immunoglobulin interference. Design and methods: Serum samples containing paraproteins from the index patient and eight additional patients were used to investigate the inte...

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Bibliographic Details
Main Authors: Michael O. Alberti, Thomas A. Drake, Lu Song
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Practical Laboratory Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551715000141