SeqEntropy: genome-wide assessment of repeats for short read sequencing.

SeqEntropy: genome-wide assessment of repeats for short read sequencing.

BACKGROUND: Recent studies on genome assembly from short-read sequencing data reported the limitation of this technology to reconstruct the entire genome even at very high depth coverage. We investigated the limitation from the perspective of information theory to evaluate the effect of repeats on s...

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Bibliographic Details
Main Authors: Hsueh-Ting Chu, William W L Hsiao, Theresa T H Tsao, D Frank Hsu, Chaur-Chin Chen, Sheng-An Lee, Cheng-Yan Kao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609794?pdf=render

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http://europepmc.org/articles/PMC3609794?pdf=render

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