Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan Induces IL-10-Producing B Cells and Hinders CD4+Th1 Immunity

Summary: The importance of Th1/interferon (IFN)-γ-mediated responses in mycobacterial infection has been well established. However, little is known about B cell-mediated immunity during Mycobacterium tuberculosis (Mtb) infection. Interleukin (IL)-10-producing B cells (B10 cells), a subset of B regul...

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Bibliographic Details
Main Authors: Chunhui Yuan, Zi-Lu Qu, Xiao-Lei Tang, Qi Liu, Wei Luo, Chun Huang, Qin Pan, Xiao-Lian Zhang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218302293