Regulation of RNA Splicing: Aberrant Splicing Regulation and Therapeutic Targets in Cancer

RNA splicing is a critical step in the maturation of precursor mRNA (pre-mRNA) by removing introns and exons. The combination of inclusion and exclusion of introns and exons in pre-mRNA can generate vast diversity in mature mRNA from a limited number of genes. Cancer cells acquire cancer-specific me...

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Bibliographic Details
Main Authors: Koji Kitamura, Keisuke Nimura
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/923