Non-monotonicity of Fano factor in a stochastic model for protein expression with sequesterisation at decoy binding sites

We present a stochastic model motivated by gene expression which incorporates unspecific interactions between proteins and binding sites. We focus on characterizing the distribution of free (i.e. unbound) protein molecules in a cell. Although it cannot be expressed in a closed form, we present three...

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Bibliographic Details
Main Authors: Michal Hojcka, Pavol Bokes
Format: Article
Language:English
Published: Biomath Forum 2017-11-01
Series:Biomath
Subjects:
Online Access:http://www.biomathforum.org/biomath/index.php/biomath/article/view/1031