Do acid suppressive drugs (pantoprazole and ranitidine) attenuate the protective effect of alendronate in estrogen-deficient osteoporotic rats?

Background: Alendronate is a drug of choice in the treatment of postmenopausal osteoporosis. Acid suppressive drugs are recently used in combination with alendronate to protect against stomach ulceration and oesophagitis occurring as serious problems in patients under this treatment. Aim of the work...

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Bibliographic Details
Main Authors: Afaf S. Osman, Dina A. Aly Labib, Abeer I. Omar
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Egyptian Rheumatologist
Online Access:http://www.sciencedirect.com/science/article/pii/S1110116417300960