Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

Trapped ion mobility (TIMS)-mass spectrometry with parallel accumulation-serial fragmentation (PASEF) facilitates high-sensitivity proteomics experiments. Here, the authors expand TIMS and PASEF to small molecules and demonstrate fast and comprehensive lipidomics of low biological sample amounts.

Bibliographic Details
Main Authors: Catherine G. Vasilopoulou, Karolina Sulek, Andreas-David Brunner, Ningombam Sanjib Meitei, Ulrike Schweiger-Hufnagel, Sven W. Meyer, Aiko Barsch, Matthias Mann, Florian Meier
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-14044-x

Internet

https://doi.org/10.1038/s41467-019-14044-x

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