Network Diffusion-Based Prioritization of Autism Risk Genes Identifies Significantly Connected Gene Modules

Network Diffusion-Based Prioritization of Autism Risk Genes Identifies Significantly Connected Gene Modules

Autism spectrum disorder (ASD) is marked by a strong genetic heterogeneity, which is underlined by the low overlap between ASD risk gene lists proposed in different studies. In this context, molecular networks can be used to analyze the results of several genome-wide studies in order to underline th...

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Bibliographic Details
Main Authors: Ettore Mosca, Matteo Bersanelli, Matteo Gnocchi, Marco Moscatelli, Gastone Castellani, Luciano Milanesi, Alessandra Mezzelani
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Genetics
Subjects:
autism spectrum disorder
biological networks
network diffusion
data integration
gene module
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00129/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00129/full

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