Brain Microstructural Changes Associated With Neurocognitive Outcome in Intracranial Germ Cell Tumor Survivors

Brain Microstructural Changes Associated With Neurocognitive Outcome in Intracranial Germ Cell Tumor Survivors

BackgroundChildhood intracranial germ cell tumor (GCT) survivors are prone to radiotherapy-related neurotoxicity, which can lead to neurocognitive dysfunctions. Diffusion kurtosis imaging (DKI) is a diffusion MRI technique that is sensitive to brain microstructural changes. This study aimed to inves...

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Bibliographic Details
Main Authors: Winnie Wan Yee Tso, Edward Sai Kam Hui, Tatia Mei Chun Lee, Anthony Pak Yin Liu, Patrick Ip, Vince Vardhanabhuti, Kevin King Fai Cheng, Daniel Yee Tak Fong, Dorita Hue Fung Chang, Frederick Ka Wing Ho, Ka Man Yip, Dennis Tak Loi Ku, Daniel Ka Leung Cheuk, Chung Wing Luk, Ming Kong Shing, Lok Kan Leung, Pek Lan Khong, Godfrey Chi-Fung Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
intracranial germ cell tumor
neurotoxicity
diffusion kurtosis imaging
brain microstructure
cognition
functional outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.573798/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.573798/full

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