Roflumilast-N-oxide induces surfactant protein expression in human alveolar epithelial cells type II.

Roflumilast-N-oxide induces surfactant protein expression in human alveolar epithelial cells type II.

Surfactant proteins (SPs) are important lipoprotein complex components, expressed in alveolar epithelial cells type II (AEC-II), and playing an essential role in maintenance of alveolar integrity and host defence. Because expressions of SPs are regulated by cyclic adenosine monophosphate (cAMP), we...

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Bibliographic Details
Main Authors: Kerstin Höhne, Stephan J Schliessmann, Andreas Kirschbaum, Till Plönes, Joachim Müller-Quernheim, Hermann Tenor, Gernot Zissel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398032?pdf=render

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http://europepmc.org/articles/PMC3398032?pdf=render

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