Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Abstract Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties. Multi-spectroscopic studies were used to st...

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Bibliographic Details
Main Authors: Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Chemistry Central Journal
Subjects:
Bovine serum albumin
Rivaroxaban
Human serum albumin
Fluorescence
Quenching
Online Access:http://link.springer.com/article/10.1186/s13065-017-0366-1

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http://link.springer.com/article/10.1186/s13065-017-0366-1

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