Noninvasive Monitoring of mRFP1- and mCherry-Labeled Oncolytic Adenoviruses in an Orthotopic Breast Cancer Model by Spectral Imaging
Genetic capsid labeling of conditionally replicative adenoviruses (CRAds) with fluorescent tags offers a potentially more accurate monitoring of those virotherapy agents in vivo. The capsid of an infectivity-enhanced CRAd, Ad5/3, delta 24, was genetically labeled with monomeric red fluorescent prote...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2010-03-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00003 |