A 3D Microfluidic Model to Recapitulate Cancer Cell Migration and Invasion

We have developed a microfluidic-based culture chip to simulate cancer cell migration and invasion across the basement membrane. In this microfluidic chip, a 3D microenvironment is engineered to culture metastatic breast cancer cells (MX1) in a 3D tumor model. A chemo-attractant was incorporated to...

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Bibliographic Details
Main Authors: Yi-Chin Toh, Anju Raja, Hanry Yu, Danny van Noort
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Bioengineering
Subjects:
Online Access:http://www.mdpi.com/2306-5354/5/2/29