Specific and Sensitive Diagnosis of BCOR-ITD in Various Cancers by Digital PCR

Specific and Sensitive Diagnosis of BCOR-ITD in Various Cancers by Digital PCR

BCOR is an epigenetic regulator altered by various mechanisms including BCOR-internal tandem duplication (BCOR-ITD) in a wide range of cancers. Six different BCOR-ITD in the 3’-part of the coding sequence of exon 15 have been reported ranging from 89 to 114 bp in length. BCOR-ITD is a common genetic...

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Bibliographic Details
Main Authors: Doriane Barets, Romain Appay, Marie Heinisch, Maxime Battistella, Corinne Bouvier, Guillaume Chotard, François Le Loarer, Nicolas Macagno, Romain Perbet, Daniel Pissaloux, Audrey Rousseau, Arnaud Tauziède-Espariat, Pascale Varlet, Alexandre Vasiljevic, Carole Colin, Frédéric Fina, Dominique Figarella-Branger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
digital PCR assay
BCOR-internal tandem duplication
diagnostic marker
HGNET-BCOR
FFPE tissue
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.645512/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.645512/full

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